SCIENTIFIC ARTICLES

ONCONSCIENCE PUBLISHED: Glycolysis, tumor metabolism, cancer growth and dissemination. A new pH-based etiopathogenic perspective and therapeutic approach to an old cancer question.

Proton channels and exchangers in cancer.

Resistance to cancer chemotherapy:failure in drug response from ADME to P-gp

An Integral approach to the etiopathogenesis of human neurodegenerative diseases (HNDDs) and cancer. Possible therapeutic consequences within the frame of the trophic factor withdrawal syndrome (TFWS).

Integrating fields of cancer research through pivotal mechanisms and synthetic final pathways: a unifying and creative overview.

Growth and trophic factors, pH and Na + / H + exchanger in Alzheimer's disease, other neurodegenerative diseases and cancer: new therapeutic possibilities and potential dangers.

A comprehensive approach to the etiopathogenesis of human neurodegenerative diseases (HNDDs) and cancer. Possible therapeutic implications within the frame of the trophic factor withdrawal syndrome (TFW) cancer.

The role of pH and dynamics / H + antiporter Na + in the etiopathogenesis and treatment of cancer. Two sides of the same coin, one single nature.

Proton dynamic cancer.

Integrating fields of cancer research through pivotal mechanisms and shyncetic final pathways: a unifying and creative overview.

Na + -H + Exchanger pH Regulation and Cancer.

Na + -H + Exchanger (NHE1) in pH Regulation and Cancer.

Cell membrane, cytosolic pH and drug transport in cancer and MDR: its physics, biochemistry, and molecular biology.

Cariporide and other new and powerful NHE1 inhibitors as potentially selective anticancer

drugs – an integral molecular/biochemical/ metabolic/clinical approach after one hundred

years of cancer research.

Hydrogen ion dynamics and the Naþ/Hþ exchanger in cancer angiogenesis and antiangiogenesis.

Proton Transport Inhibitors as Potentially Selective Anticancer Drugs.

Alkatolic disequilibrium in Patiens with Solid Tumors: Rediscovey of an Old Finding.

Edelfosine, apoptosis, MDR and Na+/H+ exchanger: Induction mechanisms and treatment implications.

Implication of Proton channels and Exchangers in Cancer 

Amiloride and its analogs Unique Cation Transport Inhibitors.

Cáncer a generalization.

Cáncer, Chemotherapy y Pharmacology.

Effects of Systemic Acidification of Mice with Sarcoma 1801.

Evolution of Cancer: Possible relatioships to Changes in Environmental Hydrogen Ion Concentration.

Experimental and Human Cancer, pH, and spontaneus regressions.

Hypercalcemia complicating childhood malignancies.

Integrated etiophathogenesis of Cancer of Mucosal surfaces with Emphais en la Digestive Tract:  And Appraisal.

Plasma Membrane Oxidoreductases in Control of An i mal and Plant Growth.

Duodenal carcinoid tumor and esophageal carcinoma associated to a high chronic intake of sodium bicarbonate. Possible pathophysiological mechanisms.

Mitogenic inhibition and effect on survival of mice bearing L1210 leukemia using a combination of dehydroascorbic acid and hydroxycobalamin.

The Na + / H + antiporter in Oncology in the light of in spontaneus regression of cancer.and Cell Metabolism.

Intra-arterial and intravenous chemotherapy for the treatment of malignant glioma.

Cervical Mosaic and a Integrated Pathophysiological Approach to Early Cervical Neoplasia.

Hierachical organization, Med Hypotheses,

Hydrogen ion dynamics and cancer. 

Unitive strategy of cancer cell. Carbohydrate metabolism (first of three parts).

Unitive strategy of cancer cells. The hydrogen ion as a Unitarian and multidimensional factor in carbohydrate metabolism (second of three parts).

Cellular acidification as a new approach to cancer treatment and tothe understanding and therapeutics of neurodegenerative diseases 2017.

“The new pH-centric anticancer paradigm in Oncology and Medicine”; SCB, 2017.